The intensity distribution in the focal region for the azimuthally polarized beam phase-encoded by the binary 0/π phase plate is calculated on the basis of the vector diffraction theory. With the annular pupil aperture employed, the resolution of the focal spot will be improved remarkably. We demonstrate a sharper focal spot with full width at half maximum (FWHM) of 0.223λ (below λ/4), significantly smaller that of linear, circular and radial polarization Asian Fit Oakley Gray Lens Gray Frame beam under the same condition. The focusing phenomena for illumination beam with various polarization status and beam shapes are analyzed explicitly. This analysis could have potential applications in confocal microscopy and two-photo microscopy for polarization difference imaging.
Activation of angiotensin II (Ang II) type 1 receptor (AT1R) signaling is reported to play an important role in Sunglasses Oakley C Six Light Blue Lens Black Frame
cardiac hypertrophy. We previously cloned a novel molecule interacting with the AT1R, which we named ATRAP (for Ang II type 1 receptor-associated protein). Here, we report that overexpression of ATRAP significantly decreases the number of AT1R on the surface of cardiomyocytes, and also decreases the degree of p38 mitogen-activated protein kinase phosphorylation, the activity of the c-fos promoter and protein synthesis
upon Ang II treatment. These results indicate that ATRAP significantly promotes downregulation of the AT1R and further attenuates certain Ang II-mediated hypertrophic responses in cardiomyocytes.